Rifu Intelligent Unveils Medical-Grade Reagent Tube Filling Production Line
Dual-Machine Synergy Creates a Full-Process Automated Closed Loop, and Dual Vibratory Bowl Feeding System Solves the Dual Challenges of Precision and Efficiency in Medical Packaging
Guangdong Rifu Intelligent Equipment Co., Ltd. (hereinafter referred to as "Rifu Intelligent") announced today that its self-developed medical-grade reagent tube filling production line has been successfully debugged and officially delivered to the market. Comprising a liquid filling and capping integrated machine and a horizontal roller labeling machine, this production line is specifically designed for high-precision filling scenarios of medical reagents and biological samples. It enables fully intelligent production processes, including empty tube feeding, quantitative filling, automatic capping, and high-speed labeling, providing high-precision and highly compliant packaging solutions for the biopharmaceutical and IVD (in vitro diagnostic) industries.
The liquid filling and capping integrated machine innovatively adopts a dual vibratory bowl feeding system:
Empty Tube Orientation and Conveying Module: A customized vibratory bowl is used to achieve disordered feeding and dynamic sorting of plastic reagent tubes. The material - contacting guide channels and distribution trays are made of food-grade 304 stainless steel. Equipped with an AI vision inspection system, it automatically rejects deformed or chipped defective products, ensuring a tube feeding pass rate of ≥99.8%.
Precision Filling Unit: Equipped with a high-precision peristaltic pump metering system imported from Germany, it supports free switching across the full range of 1 - 50ml. The filling accuracy reaches ±0.5% (CV value), which is 35% higher than traditional piston filling technology, meeting the filling requirements for trace reagents such as nucleic acid test reagents and antigen extraction solutions.
Intelligent Capping System: Another vibratory bowl realizes the automatic sorting and directional conveying of caps. Using servo-motor-driven capping technology, it monitors torque values in real-time (control accuracy ±0.1N·m). Combined with a vacuum adsorption capping device, it ensures a 100% sealing pass rate, completely solving problems such as liquid leakage and thread stripping caused by manual capping.
The horizontal roller labeling machine adopts the industry-leading three-roller pressing labeling technology:
Horizontal Dynamic Labeling Platform: An inclined conveying track is designed for small-diameter reagent tubes with a diameter of φ8 - 25mm. Through the linkage of the driving wheel, driven wheel, and pressure roller, it enables high-speed labeling of tubes while they are rolling. The labeling speed can reach 150 - 300 pieces per minute, and the labeling position accuracy is ±0.5mm, completely overcoming the industry problem of easy offset in labeling small-diameter cylindrical surfaces.
Intelligent Labeling Tape Management System: Integrated with a magnetic powder tension controller and a color mark tracking sensor, it supports seamless switching of various label materials, such as PVC, PET, and silver-coated paper. The label loss rate is ≤0.3%, significantly reducing consumable costs.
Medical-Grade Compliance Design to Meet Stringent GMP Production Standards
Clean Process Layout: The parts of the equipment that come into contact with materials are made of 316L stainless steel (for parts in contact with liquid medicine) and medical-grade POM engineering plastics, with a surface roughness of Ra≤0.8μm. It can withstand long-term erosion by disinfectants such as 75% alcohol and sodium hypochlorite solution, meeting the requirements of FDA 21 CFR Part 11 and ISO 13485 medical device quality management systems.
Full-Process Quality Traceability: Standardly equipped with MES data interfaces and electronic regulatory code encoding systems, it can collect more than 20 key parameters in real-time, including filling volume, capping torque, and labeling position. The data storage period is ≥5 years, meeting the international compliance review requirements of the EU MDR and the US FDA.
Man-Machine Safety Protection: Equipped with a triple protection mechanism including infrared light curtain protection, overload automatic shutdown, and fault sound and light alarms. The emergency response time is <0.1 seconds, ensuring the safety of operators.
Customer Test Data: Double Improvements in Capacity and Efficiency, 70% Reduction in Labor Costs
In the actual tests conducted by a leading IVD enterprise, this production line demonstrated outstanding performance:
Capacity Breakthrough: The single-shift (8-hour) production capacity reaches 43,200 pieces (25ml specification), a 50% increase compared to traditional manual lines, perfectly adapting to the emergency production needs of large-scale nucleic acid test reagents and antigen test kits.
Quality Control: The standard deviation of filling volume is controlled within ±0.15ml, the fluctuation range of capping torque is ≤±0.08N·m, and the error in label edge alignment is <0.3mm. All key indicators are more than 20% better than industry standards.
Cost Optimization: The labor cost per reagent package has decreased from 0.12 yuan to 0.036 yuan, and the labor allocation has been reduced from 8 people per shift to 2 people, significantly enhancing the customer's automation production level.
Industry Benchmark Strength: Empowered by 28 Patents, Validated by Over 3,000 Global Customers
As a leading enterprise in China's intelligent packaging equipment industry, relying on a provincial-level engineering technology research center, Rifu Intelligent has obtained a total of 28 invention patents, forming three core competitiveness:
Flexible Manufacturing Technology: The 独创 multi-specification quick-switching system can complete the specification conversion between 2ml blood collection tubes and 50ml reagent bottles within 10 minutes, meeting the production needs of the medical industry for multi-variety and small-batch production.
International Compliance Capability: The equipment has passed multiple certifications such as CE and ISO 13485. It has customized COVID-19 test kit production lines for international giants such as Thermo Fisher Scientific and Becton, Dickinson and Company, and is exported to 68 countries and regions.
Full Lifecycle Service: It provides 7×24-hour remote operation and maintenance support, and the inventory cycle of key components is ≤48 hours, ensuring a 60% reduction in customer equipment downtime.
About Rifu Intelligent
Guangdong Rifu Intelligent Equipment Co., Ltd. adheres to the concept of "flexible manufacturing + intelligent control", and has been deeply engaged in the research, development, and manufacturing of liquid/powder filling, labeling, and packaging equipment for 18 years. Its products are widely used in industries such as healthcare, food, and cosmetics. The company insists on independent innovation, investing more than 15% of its annual revenue in research and development. It has delivered more than 5,000 intelligent production lines to global customers and is a national-level specialized, refined, and innovative "little giant" enterprise.
Conclusion
The launch of this medical-grade reagent tube filling production line is another milestone for Rifu Intelligent in the high-end medical packaging field. In the future, the company will continue to focus on cutting-edge technologies such as AI vision inspection and IoT cloud platforms, providing global medical enterprises with "more precise, safer, and smarter" packaging solutions and contributing to the digital and intelligent transformation and upgrading of the biopharmaceutical industry.
